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Does it feel like no amount of rest ever restores your energy?
Do your hands tingle, your vision blurs or a wave of pain crashes over you without warning? If these struggles sound familiar, you might be dealing with more than just everyday fatigue because these are the symptoms of fibromyalgia and multiple sclerosis.
Both conditions can cause widespread discomfort and significantly impact daily life, but they have different causes and treatments.
Let’s look at these differences so that you can manage your symptoms more effectively.
ANF Therapy®️ (Amino Neuro Frequency Therapy) is the most advanced frequency-based therapy for treating various health issues without drugs and chemicals. It aims to activate the body’s natural healing process and treat the root cause of diseases instead of managing just symptoms.

What Is Fibromyalgia?
Fibromyalgia is a chronic pain condition. It impacts how your brain and spinal cord interpret pain signals. Instead of being caused by injury or inflammation, fibromyalgia stems from an overactive nervous system that misinterprets normal sensations as pain.
Along with widespread musculoskeletal pain, fibromyalgia is accompanied by crushing fatigue, restless sleep, and mental fog so thick it’s called “fibro fog”.
Research shows that fibromyalgia affects 2–8% of the global population, with women being diagnosed far more often than men.
What is MS?
MS is an autoimmune condition that involves your central nervous system. Your immune system triggers a response against the protective coating (myelin sheath) around nerve fibres in your brain and spinal cord. This damage leads to inflammation, scarring, and disrupted nerve signals.
There is a formation of lesions all over your central nervous system, which makes communication between the brain and body slower or even impossible. Over time, this can cause progressive neurological impairment.
According to the National Multiple Sclerosis Society, over 2.8 million people worldwide live with MS, with most cases first appearing between ages 20 and 40.

Fibromyalgia vs. Multiple Sclerosis: Key Differences
Both fibromyalgia and MS lead to similar symptoms, but they stem from different causes and affect the body through distinctive mechanisms.
Pathophysiology
Fibromyalgia happens when the nervous system becomes overly sensitive to pain. The brain and spinal cord amplify pain signals, making even light pressure or normal movement painful. This is due to the increase in certain chemicals, like substance P and glutamate, that heighten pain, while pain-blocking chemicals like serotonin and norepinephrine decrease. Brain scans show that people with fibromyalgia have more activity in the areas that process pain, which explains why their bodies react more strongly to it.
On the other hand, multiple sclerosis is an autoimmune illness where the body’s immune system attacks your nervous system. When myelin is damaged, nerve signals slow down and get blocked. MS doesn’t follow a single pattern. Some people develop muscle weakness and difficulty walking, while others struggle with blurred vision, dizziness, or relentless fatigue. Cognitive issues — often called “brain fog” — can make even routine tasks feel overwhelming.
Symptoms
Both conditions cause pain and fatigue, but their symptoms present differently. Fibromyalgia is characterized by widespread pain and sensory disturbances that affect multiple body systems. Common symptoms include:
- Widespread aching, burning, or stabbing pain on both sides of the body.
- Persistent exhaustion despite getting enough sleep
- “Fibro fog” causes severe difficulties with memory, focus, and mental clarity.
- Sensory sensitivity to touch, sound, and temperature.
- Frequent headaches
- Irritable bowel syndrome
- Mental health deterioration
On the other hand, MS symptoms depend on the location and severity of nerve damage. It has more diverse symptoms, such as:
- Numbness & tingling in the limbs. It usually affects one side of the body and is the first sign of MS.
- Blurry or double-vision
- Optic neuritis
- Muscle stiffness, spasticity, and weakness
- Trouble walking
- Dizziness and vertigo
- Lack of coordination
- Cognitive & mood changes
- Memory issues, depression, and anxiety
Onset of Symptoms
Fibromyalgia tends to creep in slowly, with symptoms that stick around and fluctuate in intensity but never fully go away. Multiple sclerosis, on the other hand, usually comes in waves—some days are worse, and then things ease up for a while before another flare hits. As MS progresses, those symptom-free periods get shorter, and the challenges start to build.

Location of Symptoms
Fibromyalgia pain is widespread, often affecting the neck, shoulders, back, hips, and limbs. It primarily involves muscles and soft tissues rather than nerves.
Multiple sclerosis symptoms depend on which part of the central nervous system is affected. Numbness, weakness, or coordination problems often occur in the arms, legs, or one side of the body. Visual disturbances stem from damage to the optic nerve.
Causes
The exact cause of fibromyalgia is not known, but research suggests it results from a combination of biological and environmental factors, such as:
- Central nervous system dysfunction
- Low serotonin and norepinephrine
- Overactivity of pain pathways
Meanwhile, MS occurs when the immune system mistakenly attacks nerve fibers:
- Protective myelin sheath coating breaks down.
- White blood cells attack nerve tissue and cause inflammation
- Inflammation results in hardened lesions that disrupt nerve function
Risk Factors
Certain factors can raise the risk of fibromyalgia or multiple sclerosis. Fibromyalgia is often linked to stress or injury, while MS is an autoimmune disease influenced by genetics and the environment.
Fibromyalgia Risk Factors Multiple Sclerosis Risk Factors
- Childhood difficulties
- Female sex
- Middle or older age
- Smoking
- High body mass index
- Alcohol abstinence
- Pre-existing medical disorders in adulthood
- Sleep disorders
- Headaches
- Other chronic pain conditions
- Depression
- Age between 20 and 40
- Women are twice as at risk than men
- Family history
- Epstein-Barr virus infection
- More common in Caucasians, especially those of Northern European descent
- Temperate climates
- Vitamin D deficiency
- Childhood obesity
- Autoimmune diseases
- Smoking
Can Fibromyalgia and Multiple Sclerosis Co-exist?
Yes, fibromyalgia and multiple sclerosis can occur together. People with MS were 44% more likely to develop fibromyalgia compared to the general population. Even with comorbid fibromyalgia and MS, MS-related nerve pain must be distinguished from fibromyalgia for proper treatment.
How to treat Fibromyalgia and Multiple Sclerosis?
ANF Therapy®️ (Amino Neuro Frequency Therapy) is an advanced, drug-free treatment that addresses neurological imbalances to help manage symptoms of fibromyalgia and multiple sclerosis (MS). Based on Einstein’s ideation of frequency medicine, ANF Therapy®️ utilizes frequency-charged, small, circular ANF Devices that are applied to specific areas of the body. These devices aim to restore neurological function, reduce inflammation, and activate the body’s natural healing process.
This treatment involves the following steps:
Step 1: History
Your ANF Therapist will begin with a comprehensive medical history assessment to understand your symptoms, severity, and triggers.
- For Fibromyalgia, the focus will be on pain severity, sleep disturbances, fatigue, cognitive fog, skin itching, and other sensitivities. Past treatments and co-existing conditions will also be reviewed.
- For Multiple Sclerosis (MS), the therapist will evaluate muscle weakness, numbness, tingling, spasticity, fatigue, and cognitive impairments, along with previous interventions.
Step 2: Physical Examination
After a detailed history, your ANF Therapist will conduct a thorough physical examination to assess neurological and musculoskeletal dysfunctions.
- In Fibromyalgia, your ANF Therapist will assess muscle tenderness, trigger points, posture, and nerve sensitivity to gauge the extent of nervous system dysregulation.
- In MS, the focus is on muscle tone, coordination, reflexes, nerve sensitivity, balance, and inflammation markers.
Step 3: Application of ANF Devices
After history-taking and examination, your ANF Therapist will apply ANF Devices that are designed to support your body’s neurological and biochemical functions.
Hydration is essential. Drink at least 1-2 glasses of water per hour to support detoxification and maximise the effects of therapy.
Step 4: Expected Outcome
According to Dr. Mikel H-G Hoff (Founder of ANF Therapy®️), most patients experience a significant reduction in symptoms, often noticing up to 50% improvement in their first session.
- Fibromyalgia patients may see reduced pain, itching, better sleep, and increased energy within days.
- MS patients often report better mobility, reduced muscle stiffness, improved balance, and decreased fatigue.
Individual results may vary based on disease severity and response to treatment.
Step 5: Follow-Up
Your ANF Therapist will schedule regular follow-ups to monitor your progress and adjust your treatment plan. ANF Devices need to be replaced every 72 hours for optimal results.
- Fibromyalgia treatment duration: 2-6 months, depending on severity.
- MS treatment duration: 3-12 months depending on progression and response.
Start Your Healing Journey with ANF Therapy®️
ANF Therapy®️ is the newest frequency-based approach to managing fibromyalgia and multiple sclerosis symptoms. If you’re seeking a drug-free alternative to improve your quality of life, consult an ANF Practitioner or find an ANF Therapist at www.anftherapy.com/find-clinic today!
For Healthcare Professionals
If you’re a healthcare practitioner and want to enhance your clinical skills with frequency medicine, learn more about the ANF Therapy®️ and ANF Clinical education program by visiting www.anfacademy.com.
About ANF Therapy®️
ANF Therapy®️ uses circular ANF Devices, which are applied directly on the skin after palpation and assessment by a trained ANF Therapist following the ANF Therapy®️ Method, Patented Model no. U202030252, ES1259974.
The ANF Therapy®️ purpose is the alleviation of injury and pain within minutes.
Our aim is that the patient experiences a reduction of pain and swelling, an increase in range of motion, and an improvement in quality of life related to health. Non-transdermal, non-invasive device, NO needles or chemicals are used.
Do you need help with your health issues? Have you been experiencing symptoms of Fibromyalgia and MS?
Contact us, and we will explain how we can help you!